Stem cell therapy for autism – first clinical trial

Infectious Behavior

A paper just out from the Shenzen Beike Cell Engineering Research Institute in Guangdong, China presents the first results of a proof-of-concept, safety trial of stem cell (SC) injections in 37 autistic children. The justification for this intervention is primarily that animal studies of various inflammatory conditions can be ameliorated by SC therapies, and there is good evidence of immune dysregulation in autism (as well as Rett, OCD, PANDAS and Tourette). It is not suggested that the SCs will populate the brain and participate in the circuitry.

Two types of cells were used: human cord blood mononuclear cells and umbilical cord-derived mesenchymal SCs. The first group of patients initially received the cord blood cells by intravenous infusion and then, at 5-7 day intervals, they received 3 more injections by the intrathecal (spinal) route. They also received behavioral therapy. The second group of patients two cord blood intravenous and intrathecal injections…

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